Macrophages Treated with VEGF and PDGF Exert Paracrine Effects on Olfactory Ensheathing Cell Function

Macrophages Treated with VEGF and PDGF Exert Paracrine Effects on Olfactory Ensheathing Cell Function

Glial cell transplantation using olfactory ensheathing cells (OECs) holds a promising approach for treating spinal cord injury (SCI). However, integration of OECs into the hostile acute secondary injury site requires interaction and response to macrophages. Immunomodulation of macrophages to reduce...

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Bibliographic Details
Main Authors: Souptik Basu, Indra N. Choudhury, Jia Yu Peppermint Lee, Anu Chacko, Jenny A. K. Ekberg, James A. St John
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Cells
Subjects:
growth factor
spinal cord injury
glia
phagocytosis
myelin
NF-κB
Online Access:https://www.mdpi.com/2073-4409/11/15/2408

Internet

https://www.mdpi.com/2073-4409/11/15/2408

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