Knockdown of the premature ovarian insufficiency candidate gene NUP107 in ovarian granulosa cells affects cell functions, including receptor expression and estrogen synthesis

Knockdown of the premature ovarian insufficiency candidate gene NUP107 in ovarian granulosa cells affects cell functions, including receptor expression and estrogen synthesis

Objective: Mutations in NUP107 have been discovered in patients with premature ovarian insufficiency and may have tissue-specific effects in ovarian development. However, the role of NUP107 in human granulosa cell (GC) function and female fertility still remains unknown. In this study, we used RNA i...

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Bibliographic Details
Main Authors: Xiao-Cheng Liu, Meng-Xin Han, Yan Xu, Hong-Yan Wang, Bin Li
Format: Article
Language:English
Published: Wolters Kluwer Health/LWW 2019-01-01
Series:Reproductive and Developmental Medicine
Subjects:
Estrogen; NUP107; Ovarian Granulosa Cells; Premature Ovarian Insufficiency
Online Access:http://www.repdevmed.org/article.asp?issn=2096-2924;year=2019;volume=3;issue=3;spage=133;epage=140;aulast=Liu

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http://www.repdevmed.org/article.asp?issn=2096-2924;year=2019;volume=3;issue=3;spage=133;epage=140;aulast=Liu

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