Inhibition of murine bladder cancer cell growth in vitro by photocontrollable siRNA based on upconversion fluorescent nanoparticles.

Inhibition of murine bladder cancer cell growth in vitro by photocontrollable siRNA based on upconversion fluorescent nanoparticles.

This study provides a unique approach to activate caged small interfering RNAs (siRNAs) using indirect UV light emitted by the near-infrared (NIR)-to-UV upconversion process to achieve high spatial and temporal gene interference patterns. siRNA molecules against the anti-apoptotic gene survivin was...

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Bibliographic Details
Main Authors: Huichen Guo, Dan Yan, Yanquan Wei, Shichong Han, Haisheng Qian, Yunshang Yang, Yingpeng Zhang, Xiangtao Liu, Shiqi Sun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4244081?pdf=render

Internet

http://europepmc.org/articles/PMC4244081?pdf=render

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