New protocol for kinetic assay seeding ability recovery “KASAR” from formalin-fixed paraffin-embedded tissues

New protocol for kinetic assay seeding ability recovery “KASAR” from formalin-fixed paraffin-embedded tissues

The real-time quaking-induced conversion (RT-QuIC) alpha-synuclein (aSyn) protein kinetic seeding assay has been very useful for detecting pathological aggregates in various synucleinopathies including Parkinson’s disease (PD). This biomarker assay relies on fresh frozen tissue to effectively seed a...

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Bibliographic Details
Main Authors:	Monica Hepker, Griffin Clabaugh, Huajun Jin, Anumantha G. Kanthasamy
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-01-01
Series:	Frontiers in Molecular Biosciences
Subjects:	biomarker RT-QuIC formalin-fixed kinetic assay alpha-synuclein protein aggregation
Online Access:	https://www.frontiersin.org/articles/10.3389/fmolb.2023.1087982/full

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