Innate RIG-I signaling restores antigen presentation in tumors and overcomes T cell resistance

In recent years, therapy with immune modulating antibodies, termed immune checkpoint blockade (ICB), has revolutionized the treatment of advanced metastatic melanoma, yielding long-lasting clinical responses in a subgroup of patients. But despite this remarkable progress, resistance to therapy repre...

Celý popis

Podrobná bibliografie
Hlavní autoři: Beatrice Thier, Annette Paschen
Médium: Článek
Jazyk:English
Vydáno: Shared Science Publishers OG 2021-01-01
Edice:Cell Stress
Témata:
On-line přístup:http://www.cell-stress.com/researcharticles/2021a-thier-cell-stress/