Chemically defined generation of human definitive hematopoietic stem and progenitor cells

Chemically defined generation of human definitive hematopoietic stem and progenitor cells

Summary: Here, we present a protocol to efficiently direct human pluripotent stem cells (hPSCs) into hematopoietic stem and progenitor cells (HSPCs) under a chemically defined, albumin-free system. We describe the induction of aorta-gonad-mesonephros-like hematopoiesis from hPSCs into SOX17+ hemogen...

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Bibliographic Details
Main Authors: Juhyung Jung, Yun Chang, Gyuhyung Jin, Qing Deng, Xiaojun Lance Lian, Xiaoping Bao
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:STAR Protocols
Subjects:
Cell Biology
Cell culture
Cell-based Assays
Stem Cells
Cell Differentiation
Biotechnology and bioengineering
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166722008334

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http://www.sciencedirect.com/science/article/pii/S2666166722008334

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