Hepatocyte-derived exosomal miR-146a-5p inhibits hepatic stellate cell EMT process: a crosstalk between hepatocytes and hepatic stellate cells

Abstract Recently, Salidroside (Sal) has been demonstrated to suppress hepatic stellate cell (HSC) activation, a crucial event for liver fibrosis. Moreover, Sal has been reported to decrease hepatocyte injury. A growing number of reports have indicated that the crosstalk between hepatocytes and HSCs...

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Bibliographic Details
Main Authors: Zhichao Lang, Yifei Li, Lifan Lin, Xinmiao Li, Qiqi Tao, Yuhang Hu, Menglu Bao, Lei Zheng, Zhengping Yu, Jianjian Zheng
Format: Article
Language:English
Published: Nature Publishing Group 2023-08-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01602-y