Effects of Nintedanib on the Lungs via NLRP3 in a Model of Lipopolysaccharide-induced Acute Lung Injury in Rats

Effects of Nintedanib on the Lungs via NLRP3 in a Model of Lipopolysaccharide-induced Acute Lung Injury in Rats

Aim: To demonstrate the possible protective efficacy of nintedanib, a tyrosine kinase inhibitor with demonstrated antifibrotic and antitumor activity, in a model of acute lung injury (ALI), a severe lung disease, through NLR family pyrin domain containing 3 (NLRP3) and nuclear factor kappa B (NF-κB)...

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Bibliographic Details
Main Authors: Gulchin TANRİVERDİYEVA, Pelin AYDIN, Erdem TOKTAY, Elif ÇADIRCI, Zekai HALICI
Format: Article
Language:English
Published: Galenos Yayincilik 2024-03-01
Series:Namık Kemal Tıp Dergisi
Subjects:
ali
nf-κb
nintedanib
nlrp3
tyrosine kinase inhibitor
Online Access: http://namikkemalmedj.com/archives/archive-detail/article-preview/effects-of-nintedanib-on-the-lungs-via-nlrp3-in-a-/64770

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http://namikkemalmedj.com/archives/archive-detail/article-preview/effects-of-nintedanib-on-the-lungs-via-nlrp3-in-a-/64770

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