The connection of motor improvement after deep brain stimulation in Parkinson’s disease and microstructural integrity of the substantia nigra and subthalamic nucleus

The connection of motor improvement after deep brain stimulation in Parkinson’s disease and microstructural integrity of the substantia nigra and subthalamic nucleus

Background: Nigrostriatal microstructural integrity has been suggested as a biomarker for levodopa response in Parkinson’s disease (PD), which is a strong predictor for motor response to deep brain stimulation (DBS) of the subthalamic nucleus (STN). This study aimed to explore the impact of microstr...

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Bibliographic Details
Main Authors: Marco G. Hermann, Nils Schröter, Alexander Rau, Marco Reisert, Nadja Jarc, Michel Rijntjes, Jonas A. Hosp, Peter C. Reinacher, Wolfgang H. Jost, Horst Urbach, Cornelius Weiller, Volker A. Coenen, Bastian E.A. Sajonz
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:NeuroImage: Clinical
Subjects:
Parkinson’s disease
Deep Brain Stimulation
Therapy response
Diffusion Microstructure Imaging (DMI)
Microstructural integrity
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158224000469

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http://www.sciencedirect.com/science/article/pii/S2213158224000469

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