LRRCA8A and ANO1 contribute to serum-induced VRAC in a Ca2+-dependent manners

The volume-regulated anion channel (VRAC) plays a central role in maintaining cell volume in response to osmotic stress. Leucine-rich repeat-containing 8A (LRRC8A) was recently identified as an essential component of VRAC although other Cl− channels were also suggested to contribute to VRAC. VRAC is...

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Bibliographic Details
Main Authors: Huiran Zhang, Yani Liu, Hongchao Men, Fan Zhang, Hailin Zhang
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Journal of Pharmacological Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861320300384