Inhibition of lipid synthesis by clofibrate: comparative study of human skin, rat skin, and rat liver in vitro
The effects of clofibrate (ethyl p-chlorophenoxyisobutyrate) on lipid synthesis by human skin were studied in vitro. The drug was found to inhibit lipid synthesis from [1-14C]acetate or [U-14C]glucose. While the synthesis of all classes of lipids was suppressed, inhibition of sterol synthesis was mo...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
1972-01-01
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| Series: | Journal of Lipid Research |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520394402 |