Association of the rs738409 polymorphism in <it>PNPLA3 </it>with liver damage and the development of nonalcoholic fatty liver disease

<p>Abstract</p> <p>Background</p> <p>In a genome-wide association scan, the single-nucleotide polymorphism (SNP) rs738409 in the patatin-like phospholipase 3 gene (<it>PNPLA3</it>) was strongly associated with increased liver fat content. We investigated whe...

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Bibliographic Details
Main Authors: Chayama Kazuaki, Mizusawa Seiho, Ueno Takato, Ochi Hidenori, Hyogo Hideyuki, Yoneda Masato, Hotta Kikuko, Nakajima Atsushi, Nakao Kazuwa, Sekine Akihiro
Format: Article
Language:English
Published: BMC 2010-12-01
Series:BMC Medical Genetics
Online Access:http://www.biomedcentral.com/1471-2350/11/172