Real-Life Experience of the Effects of Cladribine Tablets on Lymphocyte Subsets and Serum Neurofilament Light Chain Levels in Relapsing Multiple Sclerosis Patients

Real-Life Experience of the Effects of Cladribine Tablets on Lymphocyte Subsets and Serum Neurofilament Light Chain Levels in Relapsing Multiple Sclerosis Patients

Although cladribine induces sustained reductions in peripheral T and B lymphocytes, little is known about its effect on axonal damage reduction in multiple sclerosis (MS), which could be demonstrated by assessing the serum neurofilament light chain (sNfL) levels. We investigated the reduction/recons...

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Bibliographic Details
Main Authors: Damiano Paolicelli, Maddalena Ruggieri, Alessia Manni, Concetta D. Gargano, Graziana Carleo, Claudia Palazzo, Antonio Iaffaldano, Luca Bollo, Tommaso Guerra, Annalisa Saracino, Antonio Frigeri, Pietro Iaffaldano, Maria Trojano
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Brain Sciences
Subjects:
cladribine tablet
multiple sclerosis
neurofilament
real life
no evidence of disease activity
lymphocyte subset
Online Access:https://www.mdpi.com/2076-3425/12/12/1595

Internet

https://www.mdpi.com/2076-3425/12/12/1595

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