Fibroblast growth factor 21 is required for the therapeutic effects of Lactobacillus rhamnosus GG against fructose-induced fatty liver in mice

Objectives: High fructose feeding changes fibroblast growth factor 21 (FGF21) regulation. Lactobacillus rhamnosus GG (LGG) supplementation reduces fructose-induced non-alcoholic fatty liver disease (NAFLD). The aim of this study was to determine the role of FGF21 and underlying mechanisms in the pro...

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Bibliographic Details
Main Authors: Cuiqing Zhao, Liming Liu, Qi Liu, Fengyuan Li, Lihua Zhang, Fenxia Zhu, Tuo Shao, Shirish Barve, Yiping Chen, Xiaokun Li, Craig J. McClain, Wenke Feng
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877819306738