Krüppel-like factor 9 (KLF9) links hormone dysregulation and circadian disruption to breast cancer pathogenesis

Krüppel-like factor 9 (KLF9) links hormone dysregulation and circadian disruption to breast cancer pathogenesis

Abstract Background Circadian disruption is an emerging driver of breast cancer (BCa), with epidemiological studies linking shift work and chronic jet lag to increased BCa risk. Indeed, several clock genes participate in the gating of mitotic entry, regulation of DNA damage response, and epithelial-...

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Bibliographic Details
Main Authors: Weand S. Ybañez, Pia D. Bagamasbad
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Cancer Cell International
Subjects:
KLF9
Circadian disruption
Glucocorticoid
Estrogen
Breast cancer
Online Access:https://doi.org/10.1186/s12935-023-02874-1

Internet

https://doi.org/10.1186/s12935-023-02874-1

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