Genome-wide association study identifies TPH2 variant as a novel locus for severe CV-A6-associated hand, foot, and mouth disease in Han Chinese

Genome-wide association study identifies TPH2 variant as a novel locus for severe CV-A6-associated hand, foot, and mouth disease in Han Chinese

Background: Little is known about the association between genetic susceptibility and the severity of hand, foot, and mouth disease (HFMD) infected with coxsackievirus A6 (CV-A6). Methods: Three hundred and sixty-four CV-A6 HFMD patients were enrolled, including 115 severe and 249 mild patients. A ge...

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Bibliographic Details
Main Authors: Yu Meng, Tiantian Xiong, Rongxian Zhao, Jian Liu, Guangqing Yu, Jinrong Xiao, Ke Wang, Taishun Wu, Wenshan Fu, Huan Guo, Jiao Huang, Sheng Wei
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:International Journal of Infectious Diseases
Subjects:
Hand, foot, and mouth disease
Coxsackievirus 6
Severe
Genome-wide association study
Susceptibility
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971220305397

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http://www.sciencedirect.com/science/article/pii/S1201971220305397

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