Retroviral elements and their hosts: insertional mutagenesis in the mouse germ line.

The inbred mouse is an invaluable model for human biology and disease. Nevertheless, when considering genetic mechanisms of variation and disease, it is important to appreciate the significant differences in the spectra of spontaneous mutations that distinguish these species. While insertions of tra...

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Bibliographic Details
Main Authors: Irina A Maksakova, Mark T Romanish, Liane Gagnier, Catherine A Dunn, Louie N van de Lagemaat, Dixie L Mager
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC1331978?pdf=render