Salidroside improves the hypoxic tumor microenvironment and reverses the drug resistance of platinum drugs via HIF-1α signaling pathwayResearch in context

Salidroside improves the hypoxic tumor microenvironment and reverses the drug resistance of platinum drugs via HIF-1α signaling pathwayResearch in context

Background: Hypoxia commonly occurs in solid tumors. The hypoxia in the center of solid tumors considerably decreases the chemosensitivity of tumor cells and induces epithelial–mesenchymal transition (EMT) as well as drug resistance of antitumor drugs. Methods: Here, the effects of salidroside (Sal)...

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Bibliographic Details
Main Authors: Yuan Qin, Hui-juan Liu, Meng Li, Deng-hui Zhai, Yuan-hao Tang, Lan Yang, Kai-liang Qiao, Jia-huan Yang, Wei-long Zhong, Qiang Zhang, Yan-rong Liu, Guang Yang, Tao Sun, Cheng Yang
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396418304900

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http://www.sciencedirect.com/science/article/pii/S2352396418304900

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