Potential Autoimmunity Resulting from Molecular Mimicry between SARS-CoV-2 Spike and Human Proteins

Potential Autoimmunity Resulting from Molecular Mimicry between SARS-CoV-2 Spike and Human Proteins

Molecular mimicry between viral antigens and host proteins can produce cross-reacting antibodies leading to autoimmunity. The coronavirus SARS-CoV-2 causes COVID-19, a disease curiously resulting in varied symptoms and outcomes, ranging from asymptomatic to fatal. Autoimmunity due to cross-reacting...

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Bibliographic Details
Main Authors: Janelle Nunez-Castilla, Vitalii Stebliankin, Prabin Baral, Christian A. Balbin, Masrur Sobhan, Trevor Cickovski, Ananda Mohan Mondal, Giri Narasimhan, Prem Chapagain, Kalai Mathee, Jessica Siltberg-Liberles
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Viruses
Subjects:
vaccine design
AlphaFold2
coronavirus
molecular dynamics
machine learning
protein structure comparison
Online Access:https://www.mdpi.com/1999-4915/14/7/1415

Internet

https://www.mdpi.com/1999-4915/14/7/1415

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