Kidney and cystic volume imaging for disease presentation and progression in the cat autosomal dominant polycystic kidney disease large animal model

Abstract Background Approximately 30% of Persian cats have a c.10063C > A variant in polycystin 1 (PKD1) homolog causing autosomal dominant polycystic kidney disease (ADPKD). The variant is lethal in utero when in the homozygous state and is the only ADPKD variant known in cats. Affected cats hav...

Full description

Bibliographic Details
Main Authors: Yoshihiko Yu, Kate L. Shumway, Jodi S. Matheson, Marie E. Edwards, Timothy L. Kline, Leslie A. Lyons
Format: Article
Language:English
Published: BMC 2019-07-01
Series:BMC Nephrology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12882-019-1448-1