ACE2-containing defensosomes serve as decoys to inhibit SARS-CoV-2 infection.

Extracellular vesicles of endosomal origin, exosomes, mediate intercellular communication by transporting substrates with a variety of functions related to tissue homeostasis and disease. Their diagnostic and therapeutic potential has been recognized for diseases such as cancer in which signaling de...

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Bibliographic Details
Main Authors: Krystal L Ching, Maren de Vries, Juan Gago, Kristen Dancel-Manning, Joseph Sall, William J Rice, Clea Barnett, Alireza Khodadadi-Jamayran, Aristotelis Tsirigos, Feng-Xia Liang, Lorna E Thorpe, Bo Shopsin, Leopoldo N Segal, Meike Dittmann, Victor J Torres, Ken Cadwell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-09-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3001754