Effect of dexmedetomidine on ncRNA and mRNA profiles of cerebral ischemia-reperfusion injury in transient middle cerebral artery occlusion rats model

Effect of dexmedetomidine on ncRNA and mRNA profiles of cerebral ischemia-reperfusion injury in transient middle cerebral artery occlusion rats model

Ischemic stroke poses a significant global health burden, with rapid revascularization treatments being crucial but often insufficient to mitigate ischemia-reperfusion (I/R) injury. Dexmedetomidine (DEX) has shown promise in reducing cerebral I/R injury, but its potential molecular mechanism, partic...

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Bibliographic Details
Main Authors: Zhen Zhen Zhang, Abdul Nasir, Dong Li, Suliman Khan, Qian Bai, Feng Yuan
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-08-01
Series:Frontiers in Pharmacology
Subjects:
ischemia-reperfusion injury
dexmedetomidine
transcriptomics
non-coding RNAs
ischemic stroke
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1437445/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2024.1437445/full

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