Effect of cardiolipin on the antimicrobial activity of a new amphiphilic aminoglycoside derivative on Pseudomonas aeruginosa.

Amphiphilic aminoglycoside derivatives are promising new antibacterials active against Gram-negative bacteria such as Pseudomonas aeruginosa, including colistin resistant strains. In this study, we demonstrated that addition of cardiolipin to the culture medium delayed growth of P. aeruginosa, favor...

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Bibliographic Details
Main Authors: Jitendriya Swain, Micheline El Khoury, Julie Kempf, Florian Briée, Patrick Van Der Smissen, Jean-Luc Décout, Marie-Paule Mingeot-Leclercq
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6101366?pdf=render