MMP14 expression and collagen remodelling support uterine leiomyosarcoma aggressiveness

MMP14 expression and collagen remodelling support uterine leiomyosarcoma aggressiveness

Fibrillar collagen deposition, stiffness and downstream signalling support the development of leiomyomas (LMs), common benign mesenchymal tumours of the uterus, and are associated with aggressiveness in multiple carcinomas. Compared with epithelial carcinomas, however, the impact of fibrillar collag...

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Bibliographic Details
Main Authors: Jordi Gonzalez‐Molina, Paula Hahn, Raul Maia Falcão, Okan Gultekin, Georgia Kokaraki, Valentina Zanfagnin, Tirzah Braz Petta, Kaisa Lehti, Joseph W. Carlson
Format: Article
Language:English
Published: Wiley 2024-04-01
Series:Molecular Oncology
Subjects:
collagen
extracellular matrix
MMP14
uterine leiomyoma
uterine leiomyosarcoma
YAP
Online Access:https://doi.org/10.1002/1878-0261.13440

Internet

https://doi.org/10.1002/1878-0261.13440

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