Galectin-3 as a Potential Therapeutic Target in Tumors Arising from Malignant Endothelia

Galectin-3 as a Potential Therapeutic Target in Tumors Arising from Malignant Endothelia

Angiosarcoma (ASA) in humans, hemangiosarcoma (HSA) in dogs are deadly neoplastic diseases characterized by an aggressive growth of malignant cells with endothelial phenotype, widespread metastasis, poor response to chemotherapy. Galectin-3 (Gal-3), a p-galactoside-binding lectin implicated in tumor...

Full description

Bibliographic Details
Main Authors: Kim D. Johnson, Olga V. Glinskii, Valeri V. Mossine, James R. Turk, Thomas P. Mawhinney, Douglas C. Anthony, Carolyn J. Henry, Virginia H. Huxley, Gennadi V. Glinsky, Kenneth J. Pienta, Avraham Raz, Vladislav V. Glinsky
Format: Article
Language:English
Published: Elsevier 2007-08-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Angiosarcoma
galectin-3
chemotherapy
doxorubicin
apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S147655860780073X

Internet

http://www.sciencedirect.com/science/article/pii/S147655860780073X

Similar Items