Peripheral Inflammatory Markers TNF-α and CCL2 Revisited: Association with Parkinson’s Disease Severity

Peripheral Inflammatory Markers TNF-α and CCL2 Revisited: Association with Parkinson’s Disease Severity

One of the major mediators of neuroinflammation in PD is tumour necrosis factor alpha (TNF-α), which, similar to other cytokines, is produced by activated microglia and astrocytes. Although TNF-α can be neuroprotective in the brain, long-term neuroinflammation and TNF release can be harmful, having...

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Bibliographic Details
Main Authors: Georgia Xiromerisiou, Chrysoula Marogianni, Ioannis C. Lampropoulos, Efthimios Dardiotis, Matthaios Speletas, Panagiotis Ntavaroukas, Anastasia Androutsopoulou, Fani Kalala, Nikolaos Grigoriadis, Stamatia Papoutsopoulou
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
Parkinson’s disease
inflammation
TNF-a
CCL2
MCP-1
biomarkers
Online Access:https://www.mdpi.com/1422-0067/24/1/264

Internet

https://www.mdpi.com/1422-0067/24/1/264

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