Efficient Two-Stage Analysis for Complex Trait Association with Arbitrary Depth Sequencing Data
Sequencing-based genetic association analysis is typically performed by first generating genotype calls from sequence data and then performing association tests on the called genotypes. Standard approaches require accurate genotype calling (GC), which can be achieved either with high sequencing dept...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-03-01
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Series: | Stats |
Subjects: | |
Online Access: | https://www.mdpi.com/2571-905X/6/1/29 |