An arrayed CRISPR knockout screen identifies genetic regulators of GLUT1 expression

Abstract Glucose, a primary fuel source under homeostatic conditions, is transported into cells by membrane transporters such as glucose transporter 1 (GLUT1). Due to its essential role in maintaining energy homeostasis, dysregulation of GLUT1 expression and function can adversely affect many physio...

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Bibliographic Details
Main Authors: Yajuan Shi, Ketaki A. Katdare, Hyosung Kim, Jonah C. Rosch, Emma H. Neal, Sidney Vafaie-Partin, Joshua A. Bauer, Ethan S. Lippmann
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-48361-5