Comparison of chikungunya viruses generated using infectious clone or the Infectious Subgenomic Amplicons (ISA) method in Aedes mosquitoes.

Reverse genetics systems provide the opportunity to manipulate viral genomes and have been widely used to study RNA viruses and to develop new antiviral compounds and vaccine strategies. The recently described method called ISA (Infectious Subgenomic Amplicons) gives the possibility to rescue RNA vi...

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Bibliographic Details
Main Authors: Souand Mohamed Ali, Anubis Vega-Rúa, Jean-Sélim Driouich, Xavier de Lamballerie, Anna-Bella Failloux, Antoine Nougairède
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6023229?pdf=render