Highly blood perfused, highly metabolically active pancreatic islets may be more susceptible for immune attack

Abstract Differences in pancreatic islet susceptibility during type 1 diabetes development may be explained by interislet variations. This study aimed to investigate if heterogeneities in vascular support and metabolic activity in rat and human islets may explain why some islets are attacked earlier...

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Bibliographic Details
Main Authors: Sara Ullsten, Daniel Espes, My Quach, Malin Fex, Monica Sandberg, Per‐Ola Carlsson
Format: Article
Language:English
Published: Wiley 2020-07-01
Series:Physiological Reports
Subjects:
Online Access:https://doi.org/10.14814/phy2.14444