Thioester-containing proteins regulate the Toll pathway and play a role in Drosophila defence against microbial pathogens and parasitoid wasps

Abstract Background Members of the thioester-containing protein (TEP) family contribute to host defence in both insects and mammals. However, their role in the immune response of Drosophila is elusive. In this study, we address the role of TEPs in Drosophila immunity by generating a mutant fly line,...

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Bibliographic Details
Main Authors: Anna Dostálová, Samuel Rommelaere, Mickael Poidevin, Bruno Lemaitre
Format: Article
Language:English
Published: BMC 2017-09-01
Series:BMC Biology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12915-017-0408-0