Thioester-containing proteins regulate the Toll pathway and play a role in Drosophila defence against microbial pathogens and parasitoid wasps

Abstract Background Members of the thioester-containing protein (TEP) family contribute to host defence in both insects and mammals. However, their role in the immune response of Drosophila is elusive. In this study, we address the role of TEPs in Drosophila immunity by generating a mutant fly line,...

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Main Authors: Anna Dostálová, Samuel Rommelaere, Mickael Poidevin, Bruno Lemaitre
פורמט: Article
שפה:English
יצא לאור: BMC 2017-09-01
סדרה:BMC Biology
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גישה מקוונת:http://link.springer.com/article/10.1186/s12915-017-0408-0