Clinical Validation of an Automated Fluorogenic Factor XIII Activity Assay Based on Isopeptidase Activity

Clinical Validation of an Automated Fluorogenic Factor XIII Activity Assay Based on Isopeptidase Activity

Hereditary factor XIII (FXIII) deficiency is a rare autosomal bleeding disorder which can cause life-threatening bleeding. Acquired deficiency can be immune-mediated or due to increased consumption or reduced synthesis. The most commonly used screening test is insensitive, and widely used quantitati...

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Bibliographic Details
Main Authors: Martina Leitner, Christian Büchold, Ralf Pasternack, Nikolaus B. Binder, Gary W. Moore
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
automation
bleeding disorder
blood coagulation
clinical validation
diagnostic assay
factor XIII
Online Access:https://www.mdpi.com/1422-0067/22/3/1002

Internet

https://www.mdpi.com/1422-0067/22/3/1002

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