Systemic Inflammation and Complement Activation Parameters Predict Clinical Outcome of Severe SARS-CoV-2 Infections

Systemic Inflammation and Complement Activation Parameters Predict Clinical Outcome of Severe SARS-CoV-2 Infections

Overactivation of the complement system has been characterized in severe COVID-19 cases. Complement components are known to trigger NETosis via the coagulation cascade and have also been reported in human tracheobronchial epithelial cells. In this longitudinal study, we investigated systemic and loc...

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Bibliographic Details
Main Authors: Silke Huber, Mariam Massri, Marco Grasse, Verena Fleischer, Sára Kellnerová, Verena Harpf, Ludwig Knabl, Tatjana Heiner, Moritz Kummann, Magdalena Neurauter, Günter Rambach, Cornelia Speth, Reinhard Würzner
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Viruses
Subjects:
viral infection
complement
SARS-CoV-2
infectious disease
NETosis
tracheal fluid
Online Access:https://www.mdpi.com/1999-4915/13/12/2376

Internet

https://www.mdpi.com/1999-4915/13/12/2376

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