Fluorinated amphiphilic Poly(β-Amino ester) nanoparticle for highly efficient and specific delivery of nucleic acids to the Lung capillary endothelium

Fluorinated amphiphilic Poly(β-Amino ester) nanoparticle for highly efficient and specific delivery of nucleic acids to the Lung capillary endothelium

Endothelial cell dysfunction occurs in a variety of acute and chronic pulmonary diseases including pulmonary hypertension, viral and bacterial pneumonia, bronchopulmonary dysplasia, and congenital lung diseases such as alveolar capillary dysplasia with misalignment of pulmonary veins (ACDMPV). To co...

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Bibliographic Details
Main Authors: Zicheng Deng, Wen Gao, Fatemeh Kohram, Enhong Li, Tanya V. Kalin, Donglu Shi, Vladimir V. Kalinichenko
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-01-01
Series:Bioactive Materials
Subjects:
Poly (β-amino) esters nanoparticle
Lung microvascular endothelium
Gene delivery
Specific targeting
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X23002359

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http://www.sciencedirect.com/science/article/pii/S2452199X23002359

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