In vitro and in vivo antimalarial activity and cytotoxicity of extracts, fractions and a substance isolated from the Amazonian plant Tachia grandiflora (Gentianaceae)

In vitro and in vivo antimalarial activity and cytotoxicity of extracts, fractions and a substance isolated from the Amazonian plant Tachia grandiflora (Gentianaceae)

Tachia sp. are used as antimalarials in the Amazon Region and in vivo antimalarial activity of a Tachia sp. has been previously reported. Tachia grandiflora Maguire and Weaver is an Amazonian antimalarial plant and herein its cytotoxicity and antimalarial activity were investigated. Spectral analysi...

Full description

Bibliographic Details
Main Authors: Luiz Francisco Rocha e Silva, Emerson Silva Lima, Marne Carvalho de Vasconcellos, Ellen Suzany Pereira Aranha, David Siqueira Costa, Elba Vieira Mustafa, Sabrina Kelly Reis de Morais, Maria das Gracas Costa Alecrim, Sergio Massayoshi Nunomura, Lena Struwe, Valter Ferreira de Andrade-Neto, Adrian Martin Pohlit
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2013-06-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
amplexine (djalonenol)
decussatin
Plasmodium falciparum
Plasmodium berghei
human fibroblasts
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762013000400501&lng=en&tlng=en

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762013000400501&lng=en&tlng=en

Similar Items