PD-L1 and PD-L2 Expression in Cervical Cancer: Regulation and Biomarker Potential

PD-L1 and PD-L2 Expression in Cervical Cancer: Regulation and Biomarker Potential

PD-1/PD-L1 immune checkpoint inhibitors show potential for cervical cancer treatment. However, low response rates suggest that patient selection based on PD-L1 protein expression is not optimal. Here, we evaluated different PD-L1 detection methods and studied transcriptional regulation of PD-L1/PD-L...

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Bibliographic Details
Main Authors: Jossie Rotman, Leontine A. S. den Otter, Maaike C. G. Bleeker, Sanne S. Samuels, A. Marijne Heeren, Margaretha G. M. Roemer, Gemma G. Kenter, Henry J. M. A. A. Zijlmans, Nienke E. van Trommel, Tanja D. de Gruijl, Ekaterina S. Jordanova
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Immunology
Subjects:
cervical cancer
programmed cell death ligand 1
programmed cell death ligand 2
fluorescence in situ hybridization
RNAish
immunohistochemistry
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.596825/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.596825/full

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