Opioid Withdrawal Produces Sex-Specific Effects on Fentanyl-Versus-Food Choice and Mesolimbic Transcription
Background: Opioid withdrawal is a key driver of opioid addiction and an obstacle to recovery. However, withdrawal effects on opioid reinforcement and mesolimbic neuroadaptation are understudied, and the role of sex is largely unknown. Methods: Male (n = 13) and female (n = 12) rats responded under...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-08-01
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Series: | Biological Psychiatry Global Open Science |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S266717432100015X |