Proteomic Discovery and Validation of Novel Fluid Biomarkers for Improved Patient Selection and Prediction of Clinical Outcomes in Alzheimer’s Disease Patient Cohorts

Alzheimer’s disease (AD) is an irreversible neurodegenerative disease characterized by progressive cognitive decline. The two cardinal neuropathological hallmarks of AD include the buildup of cerebral β amyloid (Aβ) plaques and neurofibrillary tangles of hyperphosphorylated tau. The current disease-...

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Bibliographic Details
Main Authors: Shivangi Awasthi, Daniel S. Spellman, Nathan G. Hatcher
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Proteomes
Subjects:
Online Access:https://www.mdpi.com/2227-7382/10/3/26