Variations in MHC class I antigen presentation and immunopeptidome selection pathways [version 1; peer review: 3 approved]
Major histocompatibility class I (MHC-I) proteins mediate immunosurveillance against pathogens and cancers by presenting antigenic or mutated peptides to antigen receptors of CD8+ T cells and by engaging receptors of natural killer (NK) cells. In humans, MHC-I molecules are highly polymorphic. MHC-I...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
F1000 Research Ltd
2020-09-01
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| Series: | F1000Research |
| Online Access: | https://f1000research.com/articles/9-1177/v1 |