Naphthoquinone as a New Chemical Scaffold for Leishmanicidal Inhibitors of <i>Leishmania</i> GSK-3

Naphthoquinone as a New Chemical Scaffold for Leishmanicidal Inhibitors of <i>Leishmania</i> GSK-3

More than 1 billion people live in areas endemic for leishmaniasis, which is a relevant threat for public health worldwide. Due to the inadequate treatments, there is an urgent need to develop novel alternative drugs and to validate new targets to fight this disease. One appealing approach is the se...

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Bibliographic Details
Main Authors: Victor Sebastián-Pérez, Paula Martínez de Iturrate, Montserrat Nácher-Vázquez, Luis Nóvoa, Concepción Pérez, Nuria E. Campillo, Carmen Gil, Luis Rivas
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Biomedicines
Subjects:
leishmanicidal drugs
ligand-based drug discovery
hit optimization
leishmaniasis
GSK-3
Online Access:https://www.mdpi.com/2227-9059/10/5/1136

Internet

https://www.mdpi.com/2227-9059/10/5/1136

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