Date Palm Pollen Extract Avert Doxorubicin-Induced Cardiomyopathy Fibrosis and Associated Oxidative/Nitrosative Stress, Inflammatory Cascade, and Apoptosis-Targeting Bax/Bcl-2 and Caspase-3 Signaling Pathways

Doxorubicin (DOX) has a potent antineoplastic efficacy and is considered a cornerstone of chemotherapy. However, it causes several dose-dependent cardiotoxic results, which has substantially restricted its clinical application. This study was intended to explore the potential ameliorative effect of...

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Bibliographic Details
Main Authors: Samar S. Elblehi, Yasser S. El-Sayed, Mohamed Mohamed Soliman, Mustafa Shukry
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Animals
Subjects:
Online Access:https://www.mdpi.com/2076-2615/11/3/886