Establishment of autaptic culture with human-induced pluripotent stem cell-derived astrocytes

Establishment of autaptic culture with human-induced pluripotent stem cell-derived astrocytes

Summary: Although astrocytes are involved in the pathogenesis of CNS diseases, how they induce synaptic abnormalities is unclear. Currently, in vitro pathological astrocyte cultures or animal models do not reproduce human disease phenotypes accurately. Induced pluripotent stem cells (iPSCs) are repl...

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Bibliographic Details
Main Authors: Kouya Uchino, Yasuyoshi Tanaka, Sayaka Kawaguchi, Kaori Kubota, Takuya Watanabe, Shutaro Katsurabayashi, Shinichi Hirose, Katsunori Iwasaki
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:iScience
Subjects:
Biological sciences
Neuroscience
Cellular neuroscience
Cell biology
Stem cells research
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222010343

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http://www.sciencedirect.com/science/article/pii/S2589004222010343

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