The effect of therapeutic drug monitoring of risperidone and aripiprazole on weight gain in children and adolescents: the SPACe 2: STAR (trial) protocol of an international multicentre randomised controlled trial

Abstract Background Antipsychotic drugs are an important part of the treatment of irritability and aggression in children with an autism spectrum disorder (ASD). However, significant weight gain and metabolic disturbances are clinically relevant side effects of antipsychotic use in children. In the...

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Main Authors: Rebecca A. Hermans, Lisa T. Ringeling, Kajie Liang, Sanne M. Kloosterboer, Brenda C. M. de Winter, Manon H. J. Hillegers, Birgit C. P. Koch, Bram Dierckx
Format: Article
Language:English
Published: BMC 2022-12-01
Series:BMC Psychiatry
Subjects:
Online Access:https://doi.org/10.1186/s12888-022-04445-6