Systematic Development of Self-Nanoemulsifying Liquisolid Tablets to Improve the Dissolution and Oral Bioavailability of an Oily Drug, Vitamin K1

Systematic Development of Self-Nanoemulsifying Liquisolid Tablets to Improve the Dissolution and Oral Bioavailability of an Oily Drug, Vitamin K1

The purpose of this study is to improve the dissolution and oral bioavailability of an oily drug, vitamin K1 (VK1) by combination of self-nanoemulsifying and liquisolid technologies. The optimal liquid self-nanoemulsifying drug delivery systems (SNEDDS) formulation including VK1 (oil), mixture of so...

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Bibliographic Details
Main Authors: Yongtao Tong, Yuli Wang, Meiyan Yang, Jiahui Yang, Lu Chen, Xiaoyang Chu, Chunhong Gao, Qian Jin, Wei Gong, Chunsheng Gao
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Pharmaceutics
Subjects:
vitamin K1
self-emulsifying
liquisolid technology
oral drug delivery
dissolution
bioavailability
Online Access:http://www.mdpi.com/1999-4923/10/3/96

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http://www.mdpi.com/1999-4923/10/3/96

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