Cardiac Mineralocorticoid Receptor and the Na+/H+ Exchanger: Spilling the Beans

Cardiac Mineralocorticoid Receptor and the Na+/H+ Exchanger: Spilling the Beans

Current evidence reveals that cardiac mineralocorticoid receptor (MR) activation following myocardial stretch plays an important physiological role in adapting developed force to sudden changes in hemodynamic conditions. Its underlying mechanism involves a previously unknown nongenomic effect of the...

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Bibliographic Details
Main Authors: Irene Lucía Ennis, Néstor Gustavo Pérez
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
aldosterone
mineralocorticoid receptor (MR)
myocardial stretch
heart failure
NHE1
oxidative stress
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2020.614279/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2020.614279/full

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