Treatment response and outcome of children with T-cell acute lymphoblastic leukemia expressing the gamma-delta T-cell receptor

Treatment response and outcome of children with T-cell acute lymphoblastic leukemia expressing the gamma-delta T-cell receptor

T-cell malignancies expressing the γδ T-cell receptor (TCR) are often associated with poor prognosis. Here, we determined the clinical outcome of pediatric patients with T-cell acute lymphoblastic leukemia (T-ALL) expressing the γδ TCR. Of 100 newly diagnosed T-ALL patients, 93 had γδ TCR analysis p...

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Bibliographic Details
Main Authors: Ching-Hon Pui, Deqing Pei, Cheng Cheng, Suzanne L. Tomchuck, Scarlett N. Evans, Hiroto Inaba, Sima Jeha, Susana C. Raimondi, John K. Choi, Paul G. Thomas, Mari Hashitate Dallas
Format: Article
Language:English
Published: Taylor & Francis Group 2019-08-01
Series:OncoImmunology
Subjects:
γδ t cells
tcr repertoire
γδ t-all
pediatric t-all
hct
risk stratification
Online Access:http://dx.doi.org/10.1080/2162402X.2019.1599637

Internet

http://dx.doi.org/10.1080/2162402X.2019.1599637

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