LPS-induced release of IL-6 from glia modulates production of IL-1β in a JAK2-dependent manner

<p>Abstract</p> <p>Background</p> <p>Compelling evidence has implicated neuroinflammation in the pathogenesis of a number of neurodegenerative conditions. Chronic activation of both astrocytes and microglia leads to excessive secretion of proinflammatory molecules such...

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Bibliographic Details
Main Authors: Minogue Aedín M, Barrett James P, Lynch Marina A
Format: Article
Language:English
Published: BMC 2012-06-01
Series:Journal of Neuroinflammation
Subjects:
Online Access:http://www.jneuroinflammation.com/content/9/1/126