Dual-tracer positron emission tomography/computed tomography as an imaging probe of de novo lipogenesis in preclinical models of hepatocellular carcinoma

Dual-tracer positron emission tomography/computed tomography as an imaging probe of de novo lipogenesis in preclinical models of hepatocellular carcinoma

BackgroundDe novo lipogenesis is upregulated in many cancers, and targeting it represents a metabolic approach to cancer treatment. However, the treatment response is unpredictable because lipogenic activity varies greatly among individual tumors, thereby necessitating the assessment of lipogenic ac...

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Bibliographic Details
Main Authors: Chin-Ho Tsao, Rong-Hong Jhou, Chien-Chih Ke, Chun-Wei Chang, Chi-Wei Chang, Bang-Hung Yang, Wen-Sheng Huang, Bing-Fu Shih, Ren-Shyan Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Medicine
Subjects:
de novo lipogenesis
imaging probe
cancer metabolism
PET/CT
cancer therapy
lipogenesis-targeted therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.1008200/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2022.1008200/full

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