Circulating cell-free DNA-based methylation patterns for breast cancer diagnosis

Abstract Mammography is used to detect breast cancer (BC), but its sensitivity is limited, especially for dense breasts. Circulating cell-free DNA (cfDNA) methylation tests is expected to compensate for the deficiency of mammography. We derived a specific panel of markers based on computational anal...

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Bibliographic Details
Main Authors: Xianyu Zhang, Dezhi Zhao, Yanling Yin, Ting Yang, Zilong You, Dalin Li, Yanbo Chen, Yongdong Jiang, Shouping Xu, Jingshu Geng, Yashuang Zhao, Jun Wang, Hui Li, Jinsheng Tao, Shan Lei, Zeyu Jiang, Zhiwei Chen, Shihui Yu, Jian-Bing Fan, Da Pang
Format: Article
Language:English
Published: Nature Portfolio 2021-08-01
Series:npj Breast Cancer
Online Access:https://doi.org/10.1038/s41523-021-00316-7